鐣�(d膩ng)鍓嶄綅缃細 棣栭爜 > 涓タ閱�(y墨)鍩�(zh铆)妤�(y猫)/鍔╃悊閱�(y墨)甯� > 涓タ閱�(y墨)鍩�(zh铆)妤�(y猫)/鍔╃悊閱�(y墨)甯倷鑰冭硣鏂� > 2017涓タ閱�(y墨)绲�(ji茅)鍚堝煼(zh铆)妤�(y猫)鍔╃悊閱�(y墨)甯€冭│钘ョ悊瀛�(xu茅)绗簩鍗佺珷鑰冮粸瑙f瀽

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绶ㄨ集鎺ㄨ枽

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銆€銆€涓欒胺鑳�(proglumide)(鑷ㄥ簥鐢ㄥ緱涓嶅锛岄櫎闈炲叾浠栬棩鐗╀娇鐢ㄦ儏娉佷笉浣�)

銆€銆€绔剁埈鎬ц垏鑳冩硨绱犲彈楂旂祼(ji茅)鍚�.娓涘皯鑳冮吀鍒嗘硨.

銆€銆€灏嶈儍绮樿啘鏈変繚璀�(h霉)浣滅敤鍜屼績閫�(j矛n)娼扮槏鎰堝悎

銆€銆€鐢ㄤ簬鑳冩桨鐦嶃€佸崄浜屾寚鑵告桨鐦�銆佽儍鐐庛€佹€ユ€т笂娑堝寲閬撳嚭琛€

銆€銆€涓嶈壇鍙嶆噳(y墨ng)锛氭儭蹇冦€佽吂鐥涚瓑鑳冭吀閬撶櫏鐙€銆傜缍�(j墨ng)绯荤当(t菕ng)鍙嶆噳(y墨ng):闋棝銆侀牠鏆堛€佸け鐪�銆佸鍛ㄧ缍�(j墨ng)鐐庛€傚伓瑕嬬毊鐤�銆佺櫧绱�(x矛)鑳炴笡灏戙€佽娓呰綁(zhu菐n)姘ㄩ叾鍜岃喗绱呯礌鍗囬珮绛�銆�

銆€銆€璩�(zh矛)瀛愭车鎶戝埗钘�(protopump inhibitor)

銆€銆€鍙堢ūH+-K+-ATP閰舵姂鍒惰棩锛屾槸鏂板瀷鎶楁秷鍖栨€ф桨鐦嶈棩銆傜檪鏁堢⒑鍒�锛屼笉鑹弽鎳�(y墨ng)灏戯紝琚唬娉涙噳(y墨ng)鐢�銆�

銆€銆€鑷ㄥ簥甯哥敤鐨勮棩: 绗竴浠o細濂х編鎷夊攽(omeprazole)銆�

銆€銆€绗簩浠o細铇储鎷夊攽(lansoprazole)

銆€銆€绗笁浠o細娉墭鎷夊攽(pantoprazole)銆侀浄璨濇媺鍞�(rabeprazole)銆�

銆€銆€濂х編鎷夊攽 Omeprazole

銆€銆€绲�(ji茅)妲�(g貌u)鐗归粸:鑻苟鍜攽鍚″暥鐠�(hu谩n)浜炵:?锛�?锛孲鏈夋棆鍏夋€�

銆€銆€銆愯棩鐞嗕綔鐢ㄨ垏浣滅敤姗�(j墨)鍒躲€� 浣滅敤寤f硾

銆€銆€鑳僅+-K+-ATP閰跺張绋辫唱(zh矛)瀛愭车锛岀敱α鍜�β鍏╁€嬩簽鍠綅绲勬垚銆�

銆€銆€H+-K+-ATP閰舵姂鍒惰棩鑸嘓+-K+-ATP閰剁殑α浜炲柈浣嶇祼(ji茅)鍚�锛屼娇閰跺け鍘绘椿鎬э紝鎶戝埗H+鑳冮吀鍒嗘硨↓,鎶戦吀浣滅敤寮�(qi谩ng)鑰屾寔涔�銆�

銆€銆€鐠�(hu谩n)鐞冪恫(w菐ng)鏍″弸鎯呮彁渚涳細2017涓タ閱�(y墨)绲�(ji茅)鍚堝煼(zh铆)妤�(y猫)鍔╃悊閱�(y墨)甯€冭│钘ョ悊瀛�(xu茅)绗簩鍗佺珷鑰冮粸瑙f瀽銆傛杩庨粸鎿奀trl+D閫�(j矛n)琛屾敹钘�锛屼互渚块毃鏅傛煡闁�銆傚皬绶ㄥ強鏅傛洿鏂扮浉闂�(gu膩n)璩囪▕锛屾杩庢寔绾�(x霉)闂�(gu膩n)娉ㄧ挵(hu谩n)鐞冪恫(w菐ng)鏍�涓タ閱�(y墨)鍩�(zh铆)妤�(y猫)/鍔╃悊閱�(y墨)甯�鑰冭│闋婚亾銆傚鏋滄偍鍦ㄦ閬庣▼涓亣鍒颁换浣曠枒鍟忥紝璜嬬櫥閷�涓タ閱�(y墨)鍩�(zh铆)妤�(y猫)/鍔╃悊閱�(y墨)甯€冭│璜栧锛岄毃鏅傝垏寤eぇ鑰冪敓鏈嬪弸鍊戜竴璧蜂氦娴�!

绶ㄨ集鎺ㄨ枽

涓タ閱�(y墨)绲�(ji茅)鍚堝煼(zh铆)妤�(y猫)鍔╃悊閱�(y墨)甯€冭│蹇呭倷涔嬨€婂绉戝(xu茅)銆嬫骞撮珮闋昏€冮粸鍖附

2017骞翠腑瑗块啱(y墨)鍩�(zh铆)妤�(y猫)鍔╃悊閱�(y墨)甯€冭│閱�(y墨)瀛�(xu茅)鍊悊瀛�(xu茅)鍒嗙珷绛嗚鍖附

2017骞翠腑瑗块啱(y墨)绲�(ji茅)鍚堝煼(zh铆)妤�(y猫)鍔╃悊閱�(y墨)甯€冭│鍏掔瀛�(xu茅)鍚勭珷绡€(ji茅)鑰冮粸鍖附

2017涓タ閱�(y墨)鍔╃悊閱�(y墨)甯€冭│涓タ閱�(y墨)鑷ㄥ簥濠︾瀛�(xu茅)鍒嗙珷绡€(ji茅)閲嶉粸绛嗚鍖附

銆€銆€鏈枃浠嬬垂2017涓タ閱�(y墨)绲�(ji茅)鍚堝煼(zh铆)妤�(y猫)鍔╃悊閱�(y墨)甯€冭│钘ョ悊瀛�(xu茅)绗簩鍗佺珷鑰冮粸瑙f瀽鍏�(n猫i)瀹逛緵鑰冪敓鍙冮柋锛屽笇鏈涘皪鍌欒€�2017骞翠腑瑗块啱(y墨)绲�(ji茅)鍚堝煼(zh铆)妤�(y猫)鍔╃悊閱�(y墨)甯硣鏍艰€冭│鐨勮€冪敓鏈夊公鍔�銆傜挵(hu谩n)鐞冪恫(w菐ng)鏍¢毃鏅傛洿鏂颁腑瑗块啱(y墨)绲�(ji茅)鍚堝煼(zh铆)妤�(y猫)鍔╃悊閱�(y墨)甯€冭│钘ョ悊瀛�(xu茅)鑰冮粸瑙f瀽锛屾杩庤€冪敓鎸佺簩(x霉)闂�(gu膩n)娉ㄧ挵(hu谩n)鐞冪恫(w菐ng)鏍′腑瑗块啱(y墨)绲�(ji茅)鍚堝煼(zh铆)妤�(y猫)鍔╃悊閱�(y墨)甯€冭│闋婚亾銆�

銆€銆€鐩搁棞(gu膩n)鎺ㄨ枽锛�涓タ閱�(y墨)绲�(ji茅)鍚堝煼(zh铆)妤�(y猫)鍔╃悊閱�(y墨)甯€冭│鍌欒€冪稉(j墨ng)椹楀尟绺�

銆€銆€鑳冭泲鐧介叾鍒嗘硨↓

銆€銆€灏嶅菇闁€铻烘】鑿屾湁鎶戝埗浣滅敤

銆€銆€銆愯嚚搴婃噳(y墨ng)鐢ㄣ€�

銆€銆€鍙嶆祦鎬ч閬撶値锛氭湁鏁堢巼閬�(d谩)75~85%銆�

銆€銆€娑堝寲鎬ф桨鐦嶏細鏈嶇敤1~6鏈�锛屾桨鐦嶆剤鍚堢巼閬�(d谩)97%锛屽叾瀹冮钘ョ墿鐒℃晥鐢�4鍛紝鎰堝悎鐜囬仈(d谩)90%銆�

銆€銆€骞介杸铻烘】鑿屾劅鏌擄細骞介杸铻烘棆妗胯弻83%~88%杞�(zhu菐n)闄�銆�

銆€銆€涓婃秷鍖栭亾鍑鸿

銆€銆€銆愬壇浣滅敤銆�

銆€銆€1~2%闋棝銆侀牠鏆堛€佸彛骞�銆佹儭蹇�銆佽吂鑴�銆佸け鐪狅紝鍋惰鐨柟锛岀敺鎬т钩闋コ鎬у寲

銆€銆€闀锋湡鏈嶇敤锛岃儍鍏�(n猫i)绱�(x矛)鑿岄亷搴︾敓闀枫€�(鎵€浠ョ敤钘ユ檪闁撲笉瑕侀亷闀�)

銆€銆€铇储鎷夊攽 Lansoprazole

銆€銆€绗簩浠h唱(zh矛)瀛愭车鎶戝埗钘�

銆€銆€鎶戝埗鑳冮吀鍒嗘硨銆佽儍绮樿啘淇濊(h霉)鍙婃姉骞介杸铻烘】鑿屼綔鐢�

銆€銆€鎶戝埗鑳冮吀鍒嗘硨浣滅敤鍙婃姉骞介杸铻烘】鑿屼綔鐢ㄨ純濂х編鎷夊攽(omeprazole)寮�(qi谩ng)

銆€銆€绗笁浠h唱(zh矛)瀛愭车鎶戝埗钘� 娼樺鎷夊攽 (Pantoprazole) 銆侀浄璨濇媺鍞�(rabeprazole)

銆€銆€鎶楄儍閰稿垎娉屽拰鎶楀菇闁€铻烘】鑿屼綔鐢ㄥ挤(qi谩ng)

銆€銆€涓嶈壇鍙嶆噳(y墨ng)灏�

銆€銆€3) 绮樿啘淇濊(h霉)钘ucosal Protective Agents

銆€銆€澧炲挤(qi谩ng)鑳冪矘鑶滃睆闅滃姛鑳界殑钘ョ墿锛屾姷鎶楀拰闃叉鑳冮吀鍜岃儍铔嬬櫧閰剁殑渚佃潟浣滅敤

銆€銆€纭硸閶�銆佽啝楂旈墠鍔�銆佸墠鍒楄吅绱狅細鍦ㄨ儍鍏�(n猫i)褰㈡垚淇濊(h霉)鑶滐紝闃叉鑳冮吀鍜岃儍铔嬬櫧閰剁殑渚佃潟浣滅敤銆佹湁鍒╀簬灞忛殰鐨勪慨寰�(f霉)銆�

銆€銆€绫崇储鍓嶅垪閱�(misoprostol)

銆€銆€銆愯棩鐞嗕綔鐢ㄣ€�

銆€銆€鎶戝埗鍩虹(ch菙)鑳冮吀鍒嗘硨

銆€銆€鎶戝埗绲勮兒銆佽儍娉岀礌銆侀鐗╃瓑鍒烘縺寮曡捣鐨勮儍閰稿拰鑳冭泲鐧介叾鐨勫垎娉�

銆€銆€鎻愰珮绮樻恫鍜孒CO3-楣藉垎娉�

銆€銆€淇冮€�(j矛n)鑳冪矘鑶滀笂鐨窗(x矛)鑳炵殑閲嶅缓鍜屽娈�

銆€銆€澧炲姞鑳冪矘鑶滆娴�

銆€銆€銆愯嚚搴婃噳(y墨ng)鐢ㄣ€�

銆€銆€鑳冨拰鍗佷簩鎸囪吀娼扮槏锛屽苟鏈夐爯(y霉)闃插京(f霉)鐧�(f膩)浣滅敤銆�

銆€銆€灏嶉暦鏈熸噳(y墨ng)鐢ㄩ潪鐢鹃珨鎶楃値钘ュ紩璧风殑娑堝寲鎬ф桨鐦嶃€佽儍鍑鸿锛屼綔鐐虹窗(x矛)鑳炰繚璀�(h霉)钘ユ湁鐗规晥銆�

銆€銆€瀛愬鏀剁府浣滅敤锛岀敤浜庣敘(ch菐n)鍚庢琛€銆�

銆€銆€銆愪笉鑹弽鎳�(y墨ng)銆�

銆€銆€鑵圭€�銆侀牠鐥�銆侀牠鏆堢瓑銆�

銆€銆€瀛曞│鍙婂墠鍒楄吅绱犻亷鏁忚€呯鐢�銆�

銆€銆€纭硸閶� sucralfate

銆€銆€銆愯棩鐞嗕綔鐢ㄣ€�

銆€銆€鑱氬悎鎴愯啝鍑�

銆€銆€绮橀檮浜庝笂鐨窗(x矛)鑳炲拰娼扮槏鍩哄簳鑶滀笂锛屽舰鎴愭桨鐦嶄繚璀�(h霉)鑶�

銆€銆€鎶靛尽渚佃潟锛屾笡杓曠矘鑶滄悕鍌�;

銆€銆€淇冮€�(j矛n)鑳冪矘娑插拰HCO3—鐨勫垎娉岋紝淇濊(h霉)娼扮槏绮樿啘銆�

銆€銆€銆愯嚚搴婃噳(y墨ng)鐢ㄣ€�

銆€銆€娑堝寲鎬ф桨鐦�銆佸弽娴佹€ч閬撶値銆佹參鎬х硿鐖涙€ц儍鐐�銆�

銆€銆€Sucralfate鍦ㄩ吀鎬х挵(hu谩n)澧冧腑鎵嶈兘鐧�(f膩)鎻綔鐢紝鎳�(y墨ng)鍦ㄩ/鍓�1 h绌鸿吂鏈嶇敤锛�

銆€銆€鏈嶈棩鍚�30min鍏�(n猫i)绂佺敤鎶楅吀钘�銆佽儍閰稿垎娉屾姂鍒惰棩銆�

銆€銆€銆愪笉鑹弽鎳�(y墨ng)銆�

銆€銆€2%鎮h€呭彲鏈変究绉樸€�

銆€銆€鍋舵湁鍙e共銆佹儭蹇�銆佺毊鐤瑰強闋殘銆�

銆€銆€鏋告珵閰搁墠閴€( bismuthpotassium citrate )

銆€銆€瑕嗚搵浜庢桨鐦嶈〃闈㈠舰鎴愪繚璀�(h霉)灞わ紝娓涘皯鑳冮吀銆佽儍铔嬬櫧閰剁瓑灏嶆桨鐦嶉潰鐨勫埡婵€锛屼績閫�(j矛n)娼扮槏鎰堝悎銆�

銆€銆€鎶楀菇闁€铻烘】鑿屼綔鐢�

銆€銆€鐠�(hu谩n)鐞冪恫(w菐ng)鏍″弸鎯呮彁渚涳細2017涓タ閱�(y墨)绲�(ji茅)鍚堝煼(zh铆)妤�(y猫)鍔╃悊閱�(y墨)甯€冭│钘ョ悊瀛�(xu茅)绗簩鍗佺珷鑰冮粸瑙f瀽銆傛杩庨粸鎿奀trl+D閫�(j矛n)琛屾敹钘忥紝浠ヤ究闅ㄦ檪鏌ラ柋銆傚皬绶ㄥ強鏅傛洿鏂扮浉闂�(gu膩n)璩囪▕锛屾杩庢寔绾�(x霉)闂�(gu膩n)娉ㄧ挵(hu谩n)鐞冪恫(w菐ng)鏍�涓タ閱�(y墨)鍩�(zh铆)妤�(y猫)/鍔╃悊閱�(y墨)甯�鑰冭│闋婚亾銆傚鏋滄偍鍦ㄦ閬庣▼涓亣鍒颁换浣曠枒鍟�锛岃珛鐧婚寗涓タ閱�(y墨)鍩�(zh铆)妤�(y猫)/鍔╃悊閱�(y墨)甯€冭│璜栧锛岄毃鏅傝垏寤eぇ鑰冪敓鏈嬪弸鍊戜竴璧蜂氦娴�!

绶ㄨ集鎺ㄨ枽

涓タ閱�(y墨)绲�(ji茅)鍚堝煼(zh铆)妤�(y猫)鍔╃悊閱�(y墨)甯€冭│蹇呭倷涔嬨€婂绉戝(xu茅)銆嬫骞撮珮闋昏€冮粸鍖附

2017骞翠腑瑗块啱(y墨)鍩�(zh铆)妤�(y猫)鍔╃悊閱�(y墨)甯€冭│閱�(y墨)瀛�(xu茅)鍊悊瀛�(xu茅)鍒嗙珷绛嗚鍖附

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